Four actors go to a cabin in the woods to write, direct, and act in a film that will jump-start their careers. Their idea is a horror film about a man with a bag over his head, but what happens when that man mysteriously shows up?

PMS COP is the story of Mary, a police officer, who after being caught on television beating a rapist, is forced into an evil Pharmaceutical Company's drug trial for a PMS inhibitor known as Corybantic. After a tragic event Mary suffers a horrific side effect, and with her new found superhuman strength, she begins to systematically take out her vengeance on everyone in her path! Will Mary fight against her inner urge to destroy or could she become the first of a new secret weapons program designed by an evil corporation?